QUANTIFYING THE VALUE OF AN EARLY WARNING SYSTEM ON DENGUE PREVENTION

Simulation outputs

For visualization purposes, we are demonstrating the diffusion of dengue, information about dengue, and health adoption against dengue with a smaller sample size.
Final network figure

Dengue transmission and information diffusion parameters

Parameters Descriptions Values Sources

\(\nu_h\)

Transition rate from exposed to infectious state for humans 1/5 days-1
var = 0.001
Manore et al., 2015

\(\mu_h\)

Transition rate from infectious to recovered state for humans 1/6 days-1
var = 0.001
Manore et al., 2015

\(\psi_v\)

Natural per capita emergence rate of female adult mosquito emergence 1/3 Manore et al., 2015

\(\mu_v\)

Natural death rate of mosquitoes 1/40 Andraud et al., 2012

\(\nu_v\)

Transition rate from exposed to infectious state for mosquitoes 1/8 days-1 Manore et al., 2015

\(\sigma_v\)

Maximum times one mosquito bite human per day 1/2 Manore et al., 2015

\(\sigma_h\)

Maximum mosquito bites human can sustain per day 19 Manore et al., 2015

\(\beta_{hv}\)

Transmission probability between infectious mosquito and susceptible human 0.50 Andraud et al., 2012

\(\beta_{vh}\)

Transmission probability between infectious human and susceptible host 0.75 Andraud et al., 2012

\(e\)

Mosquito death rate from pesticide use 0.50 Khan et al., 2021

\(K_v\)

Mosquito carrying capacity 5000 Baseline value

\(N_h\)

Total human population 1000 Baseline value
Initially infected Percent of initial infected population 0.05 % Baseline value
Edge probability Probability two agents connect 0.03 % Baseline value
Simulation period Simulation period run-time 200 days Baseline value
Human time step Time step for agent-based model simulation 0.25 days Baseline value
Mosquito time step Time step for ODE model 0.005 days Baseline value

Attributes of individual agents

Attributes Descriptions Values
Disease State Agent occupies one of four disease states Susceptible, Exposed, Infectious or Recovered
Symptomatic Status Agent has dengue symptoms True or False
Information State Awareness of dengue circulation Uninformed or Informed
First Informed Time when agent becomes informed of dengue circulation Integer
DART Informed Number of times informed by DART Integer
Talk Informed Number of times informed by word-of-mouth communication Integer
Total Informed Total number of times informed of dengue circulation Integer
Behavior State Adoption of health-protective behavior Adopted or Not Adopted
Adoption Threshold Willingness to adopt health-protective behavior once informed 0 to 1
Mosquito Contact Reduction Efficacy Intensity of behavior adoption when reducing mosquito contact 0 to 0.7
Insecticide Efficacy Intensity of behavior adoption when using insecticide 0 to 0.8

References

  1. Anders, K.L., Nguyen, M.M.N., Tran, T.T.H., Simmons, C.P., Farrar, J., Chau, N.V.V., Wills, B., Thuy, T.T., Hung, N.T., Lien, L.B.: Epidemiological Factors Associated with Dengue Shock Syndrome and Mortality in Hospitalized Dengue Patients in Ho Chi Minh City, Vietnam. Am. J. Trop. Med. Hyg. 84(1), 127-134 (2011).
  2. Bosch, Q.A.t., Clapham, H.E., Lambrechts, L., Duong, V., Buchy, P., Althouse, B.M., Lloyd, A.L., et al.: Contributions from the Silent Majority Dominate Dengue Virus Transmission. PLoS Pathog. 14(5), e1006965 (2018).
  3. Morin, C., Semenza, J., Trtanj, J., Glass, G., Boyer, C., Ebi, K.: Unexplored Opportunities: Use of Climate- and Weather-Driven Early Warning Systems to Reduce the Burden of Infectious Diseases. Curr. Environ. Health Rep. 5, 430-438 (2018).
  4. Aguiar, M., Anam, V., Blyuss, K.B., Estadilla, C.D.S., Guerrero, B.V., Knopoff, D., Kooi, B.W., Srivastav, A.K., Steindorf, V., Stollenwerk, N.: Mathematical models for dengue fever epidemiology: A 10-year systematic review. Phys. Life Rev. 40, 65-92 (2022).
  5. Bobashev, G., Goedecke, D., Yu, F., Epstein, J.: A Hybrid Epidemic Model: Combining The Advantages Of Agent-Based And Equation-Based Approaches. In: Winter Simulation Conference (2007). pp. 1532-1537 (2007).
  6. Mao, L.: Modeling triple-diffusions of infectious diseases, information, and preventive behaviors through a metropolitan social network—An agent-based simulation. Appl. Geogr. (Sevenoaks, England) 50, 31-39 (2014).
  7. Manore, C., Hickmann, K., Hyman, J., Foppa, I., Davis, J., Wesson, D., Mores, C.: A network-patch methodology for adapting agent-based models for directly transmitted disease to mosquito-borne disease. J. Biol. Dyn. 9, 52-72 (2014)